Where Can I Buy Lysine For Cats
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Along with conventional treatments, many veterinarians prescribe L-lysine supplementation to cats suffering from respiratory problems or illnesses like the feline herpesvirus. But what is L-lysine, and does it help your cat or harm her
L-lysine has long been administered by veterinarians as a mode of prevention and treatment of feline herpesvirus, also known as FHV-1. Multiple cat foods and treats also include L-lysine as an ingredient, although care should be taken to not exceed the proper dosage for your cat. L-lysine dosages are determined per individual cat based on her weight, age, health status, and breed.
Upper respiratory illnesses may be caused by either a bacterial or viral infection, and chronic occurrences of these colds may signal the existence of FHV-1. Cats with weaker immune systems, such as kittens or senior cats, are most prone to respiratory infections and FHV-1; however, even healthy cats in their prime can fall victim to these illnesses.
Consult your veterinarian to determine if your cat is dealing with a kitty cold or a persistent bout of FHV-1. In particular, FHV-1 can be tricky, as most infected cats will overcome the initial infection, but some will develop a chronic condition. In these cats, the immune system is suppressed and FHV-1 will flare-up and cause the symptoms to start all over again.
Veterinarians typically prescribe L-lysine supplements because of a long-held assumption that the amino acid eliminates the aforementioned symptoms of the infections and also prevents future flare-ups from occurring; nearly 90% of veterinarians recommend the use of L-lysine to treat these conditions. Veterinarians were of the thought that L-lysine interfered with the replication of the FHV-1 virus by preventing the uptake of a second amino acid, arginine.
In the early 2000s, a series of research was conducted on the use of L-lysine on cats with varying and, at times, conflicting and inconclusive results. A 2003 study in the American Journal of Veterinary Research found a reduction in FHV-1 virus replication with an oral dose of 400mg of L-lysine.
However, a 2009 study, also published in the American Journal of Veterinary Research, argued that L-lysine was not an effective management tool for countering the FHV-1 virus, and might make the infection worse. The study examined a group of 261 cats and found that dietary lysine supplementation had no influence on controlling or preventing infectious upper respiratory disease amongst these felines.
Frequent use of L-lysine as a supplement lowers levels of arginine, an amino acid essential to cats; low arginine levels may cause serious health issues in felines. Arginine is responsible for critical body functions, such as kidney filtration, immune system function, hormone function, and wound healing.
Worse yet, a cat with arginine deficiency may die from hyperammonemia (ammonia intoxication), as cats are unable to synthesize arginine. Because of these conclusions, some veterinarians have reversed their position on L-lysine and no longer recommend its use on cats although it was never shown that such a severe symptom resulted from lysine administration.
Cats with digestive disorders, such as irritable bowel syndrome or ulcers, might find their chronic conditions worsened when taking L-lysine supplementation, due to negative interactions with other prescribed medications. Occasionally, a cat may develop an allergy to the L-lysine medication, resulting in difficulty breathing, dizziness, and rashes.
Because of the uncertainty surrounding its effectiveness, and the findings of the 2015 study, some veterinarians are more reluctant to prescribe L-lysine. Other doctors are waiting on new studies to be completed and results published. Until more information is available, err on the side of caution and discuss with your veterinarian whether L-lysine is right for your cat.
Procedure: Five months after primary conjunctival inoculation with FHV-1, cats were rehoused and assigned to receive 400 mg of L-lysine in food once daily for 30 days or food only. On day 15, all cats received methylprednisolone to induce viral reactivation. Clinical signs of infection were graded, and viral shedding was assessed by a polymerase chain reaction assay throughout our study. Peak and trough plasma amino acid concentrations were assessed on day 30.
Results: Fewer cats and eyes were affected by conjunctivitis, and onset of clinical signs of infection was delayed on average by 7 days in cats receiving L-lysine, compared with cats in the control group; however, significant differences between groups were not demonstrated. Significantly fewer viral shedding episodes were identified in the treatment group cats, compared with the control group cats, after rehousing but not following corticosteroid-induced viral reactivation. Mean plasma L-lysine concentration was significantly increased at 3 hours but not at 24 hours after L-lysine administration. Plasma arginine concentration was not significantly altered.
Conclusions and clinical relevance: Once daily oral administration of 400 mg of L-lysine to cats latently infected with FHV-1 was associated with reduced viral shedding following changes in housing and husbandry but not following corticosteroid administration. This dose caused a significant but short-term increase in plasma L-lysine concentration without altering plasma arginine concentration or inducing adverse clinical effects.
To determine the effectiveness of dietary lysine supplementation in cats with enzootic upper respiratory disease (URD), 50 cats were fed a ration containing 11 or 51 g lysine/kg diet for 52 days. Food intake, body weight, clinical signs, plasma amino acid concentrations and presence of Chlamydophila felis or feline herpesvirus (FHV)-1 DNA within the conjunctival fornix were assessed. Food and lysine intake of both dietary groups decreased between days 17 and 22, coinciding with peak disease and viral presence. Mean disease score for cats fed the supplemented ration (0.94) was higher than for those fed the basal diet (0.21); however, this could be attributed to a small subset of male cats which demonstrated fighting behavior that may have contributed to stress within that cage. FHV-1 DNA was detected on 12 occasions in six cats receiving the supplemented diet and on one occasion in one cat fed the basal diet. C felis DNA was never detected. Mean plasma arginine concentration was lower and plasma lysine concentration was higher in supplemented cats. Mean plasma arginine concentration declined throughout the study in both dietary groups. Data from the present study raise important questions but do not permit a definitive conclusion regarding the efficacy of dietary lysine supplementation in cats with enzootic URD.
Procedure: Cats received oral administration of lysine monohydrochloride (500 mg, q 12 h) or placebo (lactose) beginning 6 hours prior to inoculation of virus. The left conjunctival sac received a 50-microl suspension of FHV-1 grown in cell culture (1.8 X 10(8) tissue culture infective dose50) on day 1. Cats were evaluated and scores given for clinical signs each day for 21 days. Samples for virus isolation were collected from the eye and throat every third day. Plasma lysine and arginine concentrations were measured prior to the study and on days 3, 14, and 22.
Results: Cats that received lysine had less severe conjunctivitis than cats that received placebo. Virus isolation results did not differ between the groups. Plasma lysine concentration was significantly higher in cats that received lysine, compared with control cats, whereas plasma arginine concentrations did not differ between groups.
Conclusions and clinical relevance: Oral administration of 500 mg of lysine to cats was well tolerated and resulted in less severe manifestations of conjunctivitis caused by FHV-1, compared with cats that received placebo. Oral administration of lysine may be helpful in early treatment for FHV-1 infection by lessening the severity of disease.
Lysine Aid Feline Herpes Supplement is an L-Lysine supplement to aid the management of Feline Herpes (FHV-1) in kittens and cats. Lysine administration can help inhibit replication of the Feline Herpes Virus (FHV-1) and can be used to aid the management of FHV-1 infection.
The administration of Lysine has been shown to inhibit replication of the Feline Herpes Virus (FHV-1) and can be used in the management of FHV-1 infection. Lysine Aid is a very palatable and easy to give gel specifically for cats. Feline rhinotracheitis virus (feline herpesvirus type 1 or FHV-1) causes acute respiratory illness known as rhinotracheitis (or feline herpesvirus infection). The virus affects domestic and wild cats worldwide. FHV-1 is the most common viral infection affecting cats with an estimated incidence of FHV-1 of 50% of household cats.
Many humans view the amino acid lysine as a useful supplement to strengthen the absorbency of supplemental calcium and to reduce the frequency of herpes simplex outbreaks. For cat owners, this protein component is also a respected treatment for quelling herpes outbreaks, though the symptoms are quite different for felines than humans. Lysine is also different for cats than for humans in that cats require a much smaller dosage. Widely sold by the brand name Viralys, lysine is most often administered to cats as a pill or as a powder that can be camouflaged in a cat's food.
Feline herpes reveals itself as an respiratory infection for cats. Flu-like symptoms are most prevalent, including wheezing, cold sores, sneezing, fever and lethargy. Another prevalent symptom is a condition called conjunctivitis, which causes the eyes to swell and emit discharge. Though related to the human versions on the cellular level, this type of herpes cannot be transmitted to humans or other types of household pets.
Lysine for cats has a different dosage than for humans, too. Both mammals produce a certain amount that decline with age. According to the University of Maryland Medical Center, humans regularly take as much as 9,000 mg daily to end a herpes outbreak, though 1,000 mg a day is a customary daily supplement. Lysine for cats is recommended at a daily dosage of no more than 500 mg, with half that for kittens. Though the symptoms of the feline herpes will often recede with treatment within a week, various outbreaks should be expected throughout a cat's life, similar to the human versions. 59ce067264